44. Stapleton DH. The dawn of DDT and its experimental use by the Rockefeller Foundation in Mexico, 1943 1952. Parassitologia 1998; 40: 149-58. Stapleton DH. The short-lived miracle of DDT. Herit Invent Technol 2000; 15: 36-38. Russell E. War and nature: fighting humans and insects with chemicals from World War I to Silent Spring. New York: Cambridge University Press; 2001. 47. Sadusk Jr. JF to Bayne Jones S. Conference at Orlando Station of Division of Insects Affecting Man and Animals, Department of Agriculture; 1944 Mar 27. DDT general folder, box 41, USA Typhus Commission Records, Records of the Office of the Surgeon General Army ; , RG 112. College Park MD ; : National Archives. 48. Kumm HW. Malaria control west of Rome during the summer of 1944 [enclosed with Kumm HW to Strode GK, 1944 Nov 24. Rockefeller Foundation Archives, folder 101, box 12, series 700, RG 1.2. Sleepy Hollow NY ; : Rockefeller Archive Center. 49. A-20 Havoc [cited 2003 Dec 2]. Available from: URL: : edwards.af l history docs html aircraft a-20 50. Missiroli A. Anopheles control in the Mediterranean area. Proceedings of the Fourth International Congresses on Tropical Medicine and Malaria; 1948; Washington D.C. 51. Knipe FW to Leach CN, 1947 Jan 21 [enclosure]. Rockefeller Foundation Archives, folder 106, box 12, series 700, RG 1.2. Sleepy Hollow NY ; : Rockefeller Archive Center. 52. Logan JA. The Sardinian Project: an experiment in the eradication of an indigenous malarious vector. Baltimore: Johns Hopkins Press; 1953. 53. Brown PJ. Failure-as-success: multiple meanings of eradication in the Rockefeller Foundation Sardinia Project, 19461951. Parassitologia 1998; 40: 117-30. Review of ERLASS activities for 1948. Rockefeller Foundation Archives, folder 129, box 15, series 700, RG 1.2. Sleepy Hollow, NY ; : Rockefeller Archive Center. 55. ERLASS review 1949. Rockefeller Foundation Archives, folder 13, box 15, series 700, RG 1.2. Sleepy Hollow, NY ; : Rockefeller Archive Center. 56. Constantinou K. Anopheles malaria ; eradication in Cyprus. Parassitologia 1998; 40: 131-35. Litsios S. Arnoldo Galbadn's independent path for malaria control and public health in the tropics: a lost `paradigm' for WHO. Parassitologia 1998; 40: 231-3. Verhave JP. The disappearance of Dutch malaria and the Rockefeller Foundation. Parassitologia 2000; 40: 111-5. Yip K. Malaria eradication: the Taiwan experience. Parassitologia 2000; 40: 117-26. Stapleton DH. The Rockefeller Foundation's experimental strategy for using DDT for malaria control in the Caribbean region, 19411951. Proceedings of the conference on The Social History of Medicine and Public Health in the Caribbean; 2001 May 2326; University of West Indies, Cave Hill Campus, Barbadoes. 61. Birn AE. Eradication, control or neither? Hookworm!
Dr Perera was ordered to pay 25% $19 122.44 ; of the costs and expenses of the investigation, prosecution and hearing of the charge. The Tribunal further ordered publication of the hearing in the New Zealand Medical Journal. The full decisions relating to the case can be found on the Tribunal web site at mpdt .nz Reference No: 01 86D, for instance, norvasc beta.
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Prescriptions are repeatedly made, without taking any steps to reduce the danger thereof, constitutes a reckless indifference to the safety of its customers such that punitive damages are appropriate. 20. As a direct and proximate result of Meijer's acts and conduct, plaintiff has been damaged in an amount in excess of $25, 000, plus costs of suit, punitive damages, and attorney fees. COUNT V Breach of Express Warranty as to Meijer ; 21. Plaintiff incorporates the previous paragraphs of her complaint as if fully restated herein. 22. Meijer provided an express warranty on its prescription label that the bottle contained Lasix. Meijer breached that express warranty when it proved to be Norvasc. Knowing its inadequate inventory management system, and that errors in prescriptions are repeatedly made, without taking any steps to reduce the danger thereof, constitutes a reckless indifference to the safety of its customers such that punitive damages are appropriate. 23. As a direct and proximate result of Meijer's conduct, plaintiff has been damaged in an amount in excess of $25, 000, plus costs of suit, punitive damages, and attorney fees. COUNT VI Breach of the Implied Warranty of Fitness for a Particular Purpose, RC 1302.28 as to Meijer ; 24. Plaintiff incorporates the previous paragraphs of her complaint as if fully restated herein. 25. Inherent within the sale of prescription drugs by Meijer is the implied warranty of fitness for a particular purpose. Meijer knew or should have known that Lasix is a diuretic and that Nancy Gibson required it for that purpose. By providing Norfasc instead of Lasix, Meijer.
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Nicardipine Cardene ; - calcium channel blocker. Rx: hypertension. OD: hypotension, bradycardia nifedipine Procardia ; - calcium channel blocker. Rx: hypertension. OD: hypotension, bradycardia nitrazepam benzodiazepine sedative. OD: depressed LOA Nitrobid isosorbide dinitrate ; - nitrate vasodilator. Rx: angina OD: hypotension Nitrodur nitroglycerin patch ; - nitrate vasodilator. Rx: angina OD: hypotension Nitrostat nitroglycerin ; - nitrate vasodilator. Rx: angina OD: hypotension Normodyne labetalol ; - beta-blocker. Rx: angina, hypertension OD: hypotension, bradycardia Norpramin desipramine ; - tricyclic antidepressant. OD: cardiac arrest, seizures Nortriptyline Pamelor ; - tricyclic antidepressant. OD: cardiac arrest, seizures Orvasc amlodipine ; - calcium channel blocker. Rx: hypertension. OD: hypotension, bradycardia oxazepam Serax ; - benzodiazepine sedative hypnotic. Rx: anxiety. OD: respiratory depression, depressed LOA Oxycocet acetominophen + oxycodone ; - Minor analgesic + narcotic. OD: liver failure delayed ; + resp pression Oxycodan ASA + oxycodone ; NSAID with narcotic, OD: resp. alkalosis, resp. depression, seizures, bleeding, arrythmias, coma Pamelor nortriptyline ; tricyclic antidepressant. OD: cardiac arrest, seizures Paroxetine Paxil ; SSRI. Rx: depression. OD: seizures Paxil paroxetine ; SSRI. Rx: depression. OD: seizures Percocet acetominophen + oxycodone ; painkiller with narcotic. OD: liver damage, respiratory depression Percodan ASA + oxycodone ; NSAID with narcotic. OD: resp. alkalosis, resp. depression, seizures, bleeding arrythmias, coma , Phenobarbital Luminol ; barbiturate anticonvulsant. Rx: epilepsy, seizures. OD: severe resp. depression Phenytoin Dilantin ; - anticonvulsant. Rx: epilepsy, seizure disorder. OD: arrhythmias, resp. depression pindolol Visken ; beta-blocker. Rx: angina, hypertension, arrhythmias. OD: hypotension, bradycardia, hypoglycemia Plendil felodipine ; calcium channel blocker. Rx: hypertension. prazosin Minipress ; - alpha-adrenergic blocker. Rx: hypertension. Side fx: postural hypote nsion Procardia nifedipine ; calcium channel blocker. Rx: hypertension, angina propranolol Inderal ; beta-blocker. Rx: angina, hypertension, arrhythmias. OD: hypotension, bradycardia, hypoglycemia protriptyline Vivactil ; tricyclic antidepressant. OD: cardiac arrest, seizure Prozac fluoxetine ; SSRI. Rx: depression. OD: seizures quinipril Accupril ; ACE inhibitor. Rx: hypertension, CHF ramipril Altace ; ACE inhibitor. Rx: hypertension, CHF Restoril temazepam ; benzodiazepine sedative. OD: depressed LOA Rivotril clonazepam ; benzodiazepine, anticonvulsant. Rx: epilepsy, seizure disorder. Sectral acebutolol ; beta-blocker. Rx: angina, hypertension, arrhythmias Serax oxazepam ; benzodiazepine sedative. OD: depressed LOA sertaline Zoloft ; SSRI. Rx: depression. OD: seizures Serzone nefazodone ; SSRI. Rx: depression. OD: seizures Sinequan doxepin ; - tricyclic antidepressant. OD: cardiac arrest, seizures Slow potassium ; electrolyte. Rx: CHF used with diuretics & digoxin -K Sotacor sotalol ; partial beta blocker. Rx: angina, arrhythmias, hypertension Sotalol Sotacor ; partial beta blocker. Rx: angina, arrhythmia, hypertension Spironolactone Aldactone ; diuretic. Rx: hypertension, CHF Surmontil trimipramine ; tricyclic antidepressant. OD: cardiac arrest, seizures Tegretol carbamazepine ; - anticonvulsant. Rx: epilepsy, seizure disorder. OD: resp pression, coma Temezepam Restoril ; benzodiazepine sedative. OD: depressed LOA Tenormin at enolol ; beta-blocker. Rx: angina, hypertension, arrhythmias. OD: hypotension, bradycardia Terazosin Hytrin ; - alpha-adrenergic blocker. Rx: hypertension. Side fx: postural hypotension Theo-Dur, Theobid theophylline ; bronchodilator. Rx: severe asthma, COPD. OD: seizures, arrhythmias.
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Med Care. 1998 Feb; 36 2 ; : 167-79. Validity of diagnostic and drug data in standardized nursing home resident assessments: potential for geriatric pharmacoepidemiology. SAGE Study Group. Systematic Assessment of Geriatric drug use via Epidemiology. Gambassi G, Landi F, Peng L, Brostrup-Jensen C, Calore K, Hiris J, Lipsitz L, Mor V, Bernabei R. Istituto di Medicina Interna e Geriatria, Universita Cattolica del Sacro Cuore, Rome, Italy. giovanni gambassi brown OBJECTIVES: The Health Care Financing Administration requires that patients admitted to certified nursing homes be assessed with the Minimum Data Set, a data collection instrument containing more than 300 demographic, diagnostic, clinical, and treatment variables. Longterm care databases potentially may be used to assess the outcomes of specific treatments as well as drug effectiveness. The authors sought to ascertain reliability and validity of diagnostic and drug data in a database obtained by merging the Minimum Data Set with detailed information on drugs consumed by each resident. METHODS: A population of 296, 379 residents of 1, 492 nursing homes in Kansas, Maine, Mississippi, New York, and South Dakota participated in the study between 1992 and 1994. Minimum Data Set clinical diagnoses were contrasted with selected resident characteristics and a variety of symptoms and treatments. Limited to individuals who had been hospitalized in the 6 months preceding the first assessment, Minimum Data Set diagnoses were compared with those on the hospital discharge claims maintained in the Medicare Provider Analysis and Review database. Finally.
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Further, an ANDA applicant seeking approval of proposed benazepril HCl tablets would be expected to perform a fed bioequivalence study because the RLD Lotensin ; labeling states : "The extent of absorption is at least 37% as determined by urinary recovery and is not significantly influenced by the presence of food in the GI tract." An ANDA applicant seeking approval of proposed amlodipine besylate tablets would also be expected to perform a fed bioequivalence study because the RLD Norvawc ; labeling states : "The bioavailability of [amlodipine besylate tablets] is not altered by the presence of food." FDA's expectation of a fed bioequivalence study for generic versions of Lotrel is consistent with its expectation for the individual products i .e., amlodipine tablets and benazepril tablets ; . B. Reddy's Claim of "Unequal Treatment" Is Without Merit and paxil.
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Afternoon Plenary: Whose Body is This? facilitated by Roco Crdoba, California Latinas for Reproductive Justice and SisterSong Management Circle Cecelia Fire Thunder, Former Tribal President of the Oglala Sioux Tribe of South Dakota: Fighting for Abortion Rights on a Reservation Mia Mingus, Georgians for Choice: The Invisible Freak Show: Queerness, Disability, and Reproductive Justice Ghazaleh Moayedi, Arab American provider: Reproductive Justice, Abortion Rights & Young Women Dr. Stuart Berman, Centers for Disease Control: STDs Ain't Sexy: STDs and Communities of Color Deborah Arindell, American Social Health Association: What's Up with HPV and Cervical Cancer Prevention? Tara Roberts, Senior Editor, CosmoGIRL! Magazine: I the Last Virgin? What Your Mama Never Told You: Empowering Girls as Powerful Sexual Beings and penicillin.
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Other infections Various other organisms are mentioned in discussions of breastfeeding and infection, a few selected organisms are reviewed here Table 3 ; . Borrelia burgdorferi is the spirochete that causes Lyme disease. Lyme disease is characterized by multi-organ system involvement skin, heart, joints, and nervous system ; and can occur in three stages early localized, early disseminated, and late disease ; . The existence, diagnosis, and treatment of chronic Lyme disease remain highly controversial. B burgdorferi is primarily arthropod-borne and -transmitted. It is transmitted prenatally uncommonly, even in endemic areas [93], but B burgdorferi as the cause of illness in the fetus or congenital abnormalities is debated [94 96]. B burgdorferi DNA has been reported in breast milk, but there is no evidence for illness in the infant or transmission of the.
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Table 1 ; Contd. VYVA Study Ballantyne CM, et al. Heart J 2005 EASE trial Pearson TA, et al. Mayo Clin Proc 2005.
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Finally, an alternative formulation of our approach for structural characterization of proteins was carried out recently [66, 67]. This extended method [TOMOCOMD-CAMPS Computed-Aided Modeling in Protein Science ; ] was used to encompass protein stability studies by means of a combination of protein linear or quadratic indices macromolecular fingerprints ; and statistical linear and nonlinear model ; methods [66, 67]. Recently, some of present authors have proposed a new extended local bond and bond-type ; and total whole ; molecular descriptors based on the adjacency of edges and based on quadratic maps similar to those typically defined by mathematicians in linear algebra. These researchers also proposed a new matrix representation of the molecule on the "stochastic" adjacency of edges and quadratic indices derived from there. These descriptors, called bond-based quadratic indices, encode topological information given by the molecular graph, weighted by chemical information encoded in selected bond weightings. Finally, the correlation ability of the new descriptors is tested in a QSPR and QSAR studies [68]. The main objective of this work was to use non-stochastic and stochastic bond-type quadratic indices to generate predictive LDA linear discriminant analysis ; -based QSAR models enabling the selection of new hits and lead drug-like compounds with antitrichomonal activity. The in vitro and in vivo evaluation of a new lead series of heterocyclic compounds with antitrichomonal activity is also presented.
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Preventing pregnancies among married adolescents may have a long-term demographic impact. Globally, rates of population growth are more rapid in countries where women have their first child before the age of 20.8 Raising the average age at which females begin childbearing could yield substantial demographic dividends; across regions, a woman who has her first child before the age of 18 will have an average of seven children by the time she has completed childbearing as compared to a woman who waits until her early 20s to begin childbearing, who will average five or six children.6 An older age at first birth also translates into longer intervals between generations.3 Delay of first birth has contributed significantly to the fertility decline in some countries in sub-Saharan Africa. Delaying first birth can reduce maternal and infant health risks. If pregnancy occurs before adolescents are fully developed--especially in countries where anemia and malnutrition are common and where access to health care is poor8--they can be exposed to particularly acute health risks including damage to the reproductive health tract, delayed or obstructed labor, ruptures in the birth canal, and elevated risks of maternal mortality.2, 8 , Babies born to adolescents may experience more birth injuries, low birth weight and stillbirth; 15 infant mortality is highest in those countries with the largest proportions of adolescent births.3 Programs for married adolescents may fill an unmet need for family planning services. Births to married adolescents are often unplanned.6 A study in Ahmedabad, India found that most married adolescents reported that their first pregnancy was unwanted. A national survey in India found that as many as 30 percent of women age 1519 desired to delay their next birth, but were not using contraception.4 Research found that 15 percent of married 1519 year old women in Egypt and 29 percent in Pakistan expressed not wanting to become pregnant but not using contraceptives.9 Postponing childbearing beyond adolescence has benefits for young women. A woman who delays childbearing until after adolescence may gain advantages such as increased opportunities to acquire education and skills that may enable her to better care for her family and compete in the job market.6 Delayed childbearing may also be associated with young women's greater aspirations for her self and her family. Reaching married adolescents can be cost efficient, may be introduced at scale, and is sometimes less controversial than introducing programs for unmarried youth. In countries that have a strong family planning infrastructure, reorienting the program to reach married adolescents may be achieved with minimal inputs. In Bangladesh, Pathfinder found that reorienting family planning workers to conduct outreach to serve married adolescents required, for example, stopping norvasc.
In this part of our operation, we take the technology we developed in our labs our proprietary drug delivery technologies and conduct tests on our bioequivalent drug candidates against the brand name drug to evaluate the rate and extent of active drug absorption. If our generic drug's measurements are determined to meet the same standards as the brand, determined by rigid FDA bioequivalence standards eg, equivalent in the body ; , then our product is considered therapeutically equivalent to that brand and, therefore, interchangeable and ortho.
While the former combined these and other anthracyclines to cytarabine.5 Several reports confirmed that daunorubicin and idarubicin as single agents induced complete remission CR ; in 55%-88% of patients.5, 6 These CR rates appeared comparable to those reported with combination chemotherapy5 and the only randomized study comparing both approaches in the pre-ATRA era also found no statistically significant differences.7 The incorporation of ATRA, a noncytotoxic differentiating agent that is regarded as the first paradigm of molecularly targeted therapy, has changed dramatically the management, outcome, and prognosis of APL, especially when ATRA is combined with anthracycline-based chemotherapy. More recently, arsenic trioxide ATO ; has been included in the armamentarium of active drugs in APL, being perhaps the most active single agent.8 This review covers current strategies for the treatment of APL and highlights management issues encountered in the clinical practice that can be crucial for the outcome of individual patients. The potential role and place of newer agents in both front-line and salvage therapy will also be discussed. 147.
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